prikaz prve stranice dokumenta Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma
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Scientific paper - Original scientific paper
Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma
Pathology - Research and Practice, 239 (2022); 154170. https://doi.org/10.1016/j.prp.2022.154170
Pavlov, Katarina Horvat; Tadić, Vanja; Palković, Pamela Bašić; Sasi, Biljana; Magdić, Nives; Petranović, Matea Zajc; Klasić, Marija; Hančić, Suzana; Gršković, Paula; Matulić, Maja; Gašparov, Slavko; Dominis, Mara; Korać, Petra

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Pavlov, K. H., Tadić, V., Palković, P. B., Sasi, B., Magdić, N., Petranović, M. Z. ... Korać, P. (2022). Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma. Pathology - Research and Practice, 239., 154170. doi: 10.1016/j.prp.2022.154170

Pavlov, Katarina Horvat, et al. "Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma." Pathology - Research and Practice, vol. 239, 2022, p. 154170. https://doi.org/10.1016/j.prp.2022.154170

Pavlov, Katarina Horvat, Vanja Tadić, Pamela Bašić Palković, Biljana Sasi, Nives Magdić, Matea Zajc Petranović, Marija Klasić, et al. "Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma." Pathology - Research and Practice 239 (2022): 154170. https://doi.org/10.1016/j.prp.2022.154170

Pavlov, K. H., et al. (2022) 'Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma', Pathology - Research and Practice, 239, p. 154170. doi: 10.1016/j.prp.2022.154170

Pavlov KH, Tadić V, Palković PB, Sasi B, Magdić N, Petranović MZ, and sur.. Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma. Pathology - Research and Practice [Internet]. 2022 November [cited 2024 December 13];239:154170. doi: 10.1016/j.prp.2022.154170

K. H. Pavlov, et al., "Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma", Pathology - Research and Practice, vol. 239, p. 154170, November 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:264:495235. [Accessed: 13 December 2024]

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Title (english)Different expression of DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN and EP300 genes in lymphomagenesis of low vs. high grade lymphoma
AuthorKatarina Horvat Pavlov
AuthorVanja Tadić
AuthorPamela Bašić Palković
AuthorBiljana Sasi
AuthorNives Magdić
AuthorMatea Zajc Petranović
AuthorMarija Klasić
AuthorSuzana Hančić https://orcid.org/0000-0001-7864-7996
AuthorPaula Gršković
AuthorMaja Matulić
AuthorSlavko Gašparov
AuthorMara Dominis
AuthorPetra Korać
Author's institution(Merkur University Hospital)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Tumour cells develop by accumulating changes in the genome that result in changes of main cellular processes. Aberrations of basic processes such as replication and chromatin reassembly are particularly important for genomic (in)stability. The aim of this study was to analyse the expression of genes whose products are crucial for the regulation of replication and chromatin reassembly during lymphomagenesis (DNMT1, PCNA, MCM2, CDT1, EZH2, GMNN, EP300). Non-tumour B cells were used as a control, and follicular lymphoma (FL) and the two most common groups of diffuse large B cell lymphoma (DLBCL) samples were used as a model for tumour progression. The results showed that there are significant changes in the expression of the analysed genes in lymphomagenesis, but also that these changes do not display linearity when assessed in relation to the degree of tumour aggression. Additionally, an integrated bioinformatics analysis of the difference in the expression of selected genes between tumour and non-tumour samples, and between tumour samples (FL vs. DLBCL) in five GEO datasets, did not show a consistent pattern of difference among the datasets
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titlePathology - Research and Practice
Numberingvol. 239, p. 154170
p-ISSN0344-0338
DOIhttps://doi.org/10.1016/j.prp.2022.154170
URN:NBNurn:nbn:hr:264:495235
Publication2022-11
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S0344033822004149
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2024-12-10 08:12:45