prikaz prve stranice dokumenta Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.
  Preuzmi
PDF 43.22 KB
Ostalo - Sažetak s konferencije
Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.
U: Bone. Elsevier, 2009. str. S290. https://doi.org/10.1016/j.bone.2009.03.523
Kusec, Vesna; Jadrijevic, Stipislav; Staresinic, Mario; Skopljanac, Andrija; Kocman, Branislav

Citiranost:
,
Citirajte ovaj rad

Kusec, V., Jadrijevic, S., Staresinic, M., Skopljanac, A. i Kocman, B. (2009). Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.. Bone (str. S290). Elsevier. doi: 10.1016/j.bone.2009.03.523

Kusec, Vesna, et al. "Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.." Bone, Elsevier, 2009, str. S290. https://urn.nsk.hr/urn:nbn:hr:264:312492

Kusec, Vesna, Stipislav Jadrijevic, Mario Staresinic, Andrija Skopljanac i Branislav Kocman. "Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.." U Bone, S290. Elsevier, 2009. Citirano 02.04.2025.. https://urn.nsk.hr/urn:nbn:hr:264:312492

Kusec, V., et al. (2009) 'Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.', Bone, Elsevier, str. S290. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:264:312492 (Datum pristupa: 02.04.2025.)

Kusec V, Jadrijevic S, Staresinic M, Skopljanac A, Kocman B. Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.. Bone. Elsevier; 2009. Str. S290-S290. [pristupljeno 02.04.2025.] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:264:312492

V. Kusec, S. Jadrijevic, M. Staresinic, A. Skopljanac i B. Kocman, "Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.", Bone Elsevier, 2009. [Online] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:264:312492 [Citirano: 02.04.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:264:312492
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)Bone turnover disorder and osteopenia/osteoporosis after liver transplantation – preliminary report.
AutorVesna Kusec
AutorStipislav Jadrijevic
AutorMario Staresinic
MBZ: 246312
AutorAndrija Skopljanac
AutorBranislav Kocman
Autorova ustanova(Klinička bolnica Merkur)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Sažetak (engleski)
Chronic liver disease and liver transplantation may cause hepatic osteodystrophy due to many risk factors, e.g. malnutrition, immobility, hypogonadism and immunosupressants. Reduced bone formation and increased resorption contribute to osteoporosis and fractures after liver transplantation. The aim of this study was to investigate bone metabolism after liver transplantation. Patients and methods – Bone markers were measured in in 35 liver transplant recipients (32-59 years) on day 0 and 14, 3... Više months and 6 months after surgery. DEXA (L1-L4, left hip) was performed at 6 months in 20 patients. Bone markers measured: osteocalcin (OC), procollagen 1 propeptide (P1CP), beta crosslaps (CS), bone alkaline phosphatase (BAP) and osteoprotegerin (OPG). Immunosupressive therapy included corticosteroids, tacrolimus and mycophenolat mofetil. Results – Initially CS was high, BAP and P1CP were moderately increased, and OC decreased. BAP and OC increased significantly (paired Wilcoxon test) in the follow-up period, alhtough OC remained low. P1CP normalised in the first three months and CS after 6 months, both changes were significant. Osteoprotegerin decreased by half after 14 days (p<0.01) and remained during this period. Osteoporosis of both sites was found in 3 (M), osteopenia in 8 (5M, 3 F) and osteopenia of hip only in 2 patients (1M, 1F). No differences between sexes for bone markers or densitometry T-scores were found. These results indicate disorder of bone turnover after liver transplantation. Bone resorption was increased and also OPG . Differences were observed for bone formation markers, BAP and P1CP were moderately or initially increased, but OC was decreased. This finding can not be explained by differences in clearance routes of bone formation markers. Conclusions - Increased bone resorption normalised within 6 months after liver transplantation. Bone formation markers did not unequivocally indicate decreased, increased or normal osteoblast activity, and it remains to be further investigated. Bone turnover imbalance together with high incidence of osteoporosis and osteopenia (11/20) after liver transplantation points to skeletal impairment. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeOstalo - Sažetak s konferencije
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov zbornikaBone
Brojčani podacivol. 44, str. S290
p-ISSN8756-3282
DOIhttps://doi.org/10.1016/j.bone.2009.03.523
URN:NBNurn:nbn:hr:264:312492
Datum objave publikacije2009
ProjektŠifra: 214-1080229-0163
Naziv (hrvatski): Zajednička molekularna osnova etiopatogeneza koštanih poremećaja u ljudi (Kušec, Vesna, MZOS ) ( CroRIS)
Pravna nadležnost: Hrvatska
Financijer: MZOS
SkupNaziv: 36th European Symposium on Calcified Tissues
Lokacija: Beč, Austrija
Datum početka: 2009-05-23
Datum završetka: 2009-05-27
Vrsta izlaganja: Predavanje
URL dokumentahttps://www.sciencedirect.com/science/article/pii/S8756328209007704?via%3Dihub
Vrsta resursaTekst
IzdavačElsevier
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-02-02 13:49:39
accessibility

closePristupačnostrefresh

Ako želite spremiti trajne postavke, kliknite Spremi, ako ne - vaše će se postavke poništiti kad zatvorite preglednik.